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Perez cautions that "most people tolerate probiotics fine, but they still aren't risk-free." He notes that people with irritable bowel syndrome (IBS) or small intestinal bacterial overgrowth (SIBO), or who are immunocompromised, should be cautious with any probiotic and only take one under the guidance of a health care professional

It is effective for brightening the skin and fading away sun spots (hyperpigmentation)

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Dosing is adjusted progressively rather than maximized immediately, which reduces the likelihood of adverse reactions