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2.Limitations of CagriSema While preliminary results are encouraging, the combination of cagrilintide and semaglutide suffers from multiple limitations
Largest reductions (18-20%) occurred in the high-dose group after 1 and 2 weeks Combined dose groups significantly reduced the ratio by 14% after 1 and 2 weeks The decreases observed in oxidized:reduced GSH as a result of oral liposomal GSH supplementation are likely indicative of a general systemic reduction in oxidative stress levels. Plasma levels of 8-isoprostane (a marker of oxidative stress) decreased after liposomal glutathione supplementation
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10.1042/bj20110544 Biochem
