doi:10.1089/cap.2014.0026CrossRefGoogle ScholarPubMed Harfterkamp, M, Buitelaar, JK, Minderaa, RB, van de Loo-Neus, G, van der Gaag, RJ, Hoekstra, PJ
Obese people in general are more prone to suicidal ideation, making it difficult to attribute any suicidal ideation to drugs unless a study using a direct comparison between obese patients on and off GLP1R agonists is completed.[66][67] Conclusion GLP-1 Drugs work for their intended purpose and will likely represent a revolution in the way obesity is treated as well as obesity rates in the developed world
Evidence suggests that these medications exert protective effects through multiple physiological pathways, including modest reductions in systolic blood pressure, improvements in lipid metabolism, attenuation of inflammatory signaling, delayed gastric emptying, and significant weight reduction
Rather than just regulating nitric oxide, it has been associated with improved workout endurance, more stable recovery patterns, and enhanced adaptation to training stress