In addition, although statistical significance could not be calculated for values below detection limits, acetyl-CoA and ATP levels can be considered to have increased upon L-carnitine administration, which suggests that oxidation of lipids was enhanced to produce acetyl-CoA, resulting in ATP production (Table 1)
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Microglia are activated by the increased production of pro-inflammatory and anti-inflammatory cytokines, chemokines, and other inflammatory molecules, and increased glutamate release, all of which remain in microglia (Norden et al., 2015)
