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The researchers believe svL4 serves as a substrate for transglutaminases (TGMs), enabling cross-linking of structural proteins to reconstruct a functional stratum corneum
first discovered plasma intestinal flora-dependent small molecule metabolic spectrum by metabonomics and found that the plasma levels of TMAO and its precursors, choline and betaine, can predict the risk of human cardiovascular disease, thus identifying a novel relationship between intestinal flora and metabolic health (7)
Clinical judgment remains essential for patient selection, dose titration, and monitoring hypoglycemia risk
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