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The carbohydrate induced SCFA such as rectal butyric acid treatment significantly enhanced intestinal motility and alleviated stomach pain or discomfort [27]
Clinical safety and signals to monitor The most frequent side effects under MT-II and PT-141 are nausea (dose-dependent, related to central MC4R activation), hot flashes , fatigue , and for MT-II marked hyperpigmentation of skin, pre-existing nevi and mucosae
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