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For example, SGLT2i use leads to a 33% reduction (95% CI 26, 38) in hospitalisation for heart failure (HF) and a 35% reduction (95% CI 19, 47) in the incidence of end-stage kidney disease (ESKD) [3, 4], and GLP-1 RA use leads to a 10% reduction (95% CI 2, 17) in myocardial infarction (MI) and a 17% reduction (95% CI 8, 24) reduction in stroke [2]

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Approved uses and off-label benefits Ozempics approved indications are specific: It is approved to lower blood glucose in patients who have type 2 diabetes and to reduce the risk of major cardiovascular events (like heart attack or stroke) in patients who have diabetes mellitus and heart disease

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