Relaxin-3, a member of the relaxin peptide family predominantly expressed in the nucleus incertus, signals through the RXFP3 receptor and has been shown to stimulate food intake, alter stress responsiveness, and influence arousal states in animal models ( While its orexigenic effects may appear counterintuitive in the context of obesity treatment, relaxin-3 biology highlights an underappreciated dimension of appetite regulation: the integration of feeding behavior with emotional and cognitive states
Masini, A., Ceccarelli, D., Trenti, T., Gallesi, D
While carnitine is generally safe, some research suggests it may be pro-atherogenic, but additional long-term trials assessing its effects on the cardiovascular system are necessary.
Alternatively, you can take levothyroxine consistently at bedtime (3-4 hours after your last meal) to avoid morning timing conflicts