Many people experience some side effects, especially in the first few weeks
Regular follow-up with the diabetes care team, including monitoring of HbA1c, renal function, and cardiovascular risk factors, is essential to ensure that glycaemic targets are achieved and that any new treatment is well tolerated
In a Phase II trial, patients in the Mazdutide group saw a weight decrease between 5% and 22.5%, with a notable proportion of patients across different dosage groups achieving at least a 10% or even higher degree of weight reduction
Efficacy and Safety of Once-Weekly Semaglutide Monotherapy Versus Placebo in Patients With Type 2 Diabetes (SUSTAIN 1): A Double-Blind, Randomised, Placebo-Controlled, Parallel-Group, Multinational, Multicentre Phase 3a Trial