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The FDA recently approved one of these, elamipretide, for the treatment of a rare genetic mitochondrial disorder
16,23,24 Moreover, in cancer cell lines (Table 1), increased expression levels of xCT were found to be associated with increased intracellular levels of glutathione and cisplatin resistance
According to our data, SGLT-2 inhibitors show the highest probability to be superior to GLP-1RA and DPP-4 inhibitors in terms of HHF and the composite renal outcome, while GLP1-RA are superior to DPP-4 inhibitors for both outcomes
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