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In the first step, cysteine and glutamate are linked in a reaction catalyzed by the -glutamylcysteine synthase (-GCS) to form -glutamylcysteine
The oral glutathione supplement was slightly beneficial for skin lightening in particular subgroups, but the results were not statistically significant
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Causes: Venoocclusive disease: Chemotherapeutic agents, bush tea Peliosis hepatis: Anabolic steroids Hepatic vein thrombosis: Oral contraceptives Neoplasm [edit] Neoplasms have been described with prolonged exposure to some medications or toxins
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