Shortening the current cycle and extending the washout is the correct response, not increasing the dose
In a recent clinical trial, local injections of steroids (maximum three times at 4-week intervals) combined with exercise showed better outcomes in the treatment of tendinopathy than with placebo injections and exercise at 6 months ( in vivo study, dexamethasone alone did not influence the maximum stress of Achilles tendons after 15 times of its administration
Nonetheless, this work has identified novel findings that support future studies to determine whether microbiome changes are contingent upon the combination of both NNMTi and LD switch and mediated through direct NNMTi-driven mechanisms or through indirect mechanisms such as weight or fat loss 8,13
Recently, to approach particular skin wound therapy, we and others reviewed the significance of its beneficial effect on muscle, tendon, ligament, and bone injuries (Seiwerth et al., 2018)