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J Cardiovasc Dev Dis
A prespecified analysis of pooled data from the STEP-HFpEF and STEP-HFpEF DM trials demonstrated that significantly more patients treated with Wegovy 2.4 mg SC once weekly had an improvement of at least one in New York Heart Association (NYHA) functional class compared to those who received placebo (32.6% versus 21.5%, respectively
Variants in genes like PER2 (circadian rhythm) and COMT (stress metabolism) can affect how sensitive you are to semaglutide's systemic effects
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