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Real-world evidence assessment of the risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide
It is important to note that both orforglipron and oral semaglutide require daily administration (compared to weekly administration for the injectable drugs), and this raises the question of ideal dosing frequency for patient convenience
Its mechanism is relevant to general visceral adiposity but no large RCT confirms equivalent effect in metabolically healthy adults
It can also be taken by adults with a BMI equal to or more than 27 if they have a known weight-related condition
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