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Nausea, jaundice, dark urine, pale stool, severe abdominal pain, confusion, swelling or rapidly worsening fatigue require medical evaluation rather than more supplements or fasting

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You start at 0.25 mg weekly for the first four weeks, then increase to 0.5 mg for weeks 5 through 8, then 1 mg for weeks 9 through 12, then 1.7 mg for weeks 13 through 16, and finally the maintenance dose of 2.4 mg from week 17 onward