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"The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator"

FOXO4-DRI functions as a competitive inhibitor, displacing p53 from FOXO4, thereby allowing the selective clearance of senescent cells (2, 9)

That single added residue is the difference between it and the unmodified HGH Fragment 176-191, and it was introduced to improve stability and handling rather than to alter the activity, which makes the two a clean structural pair