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Growth and apoptosis Ex-4 significantly improves the survival of rat cortical neurons under oxygen/glucose deprivation (OGD) conditions through reduced apoptosis rates, increased expression of glucose-regulated protein 78, and decreased levels of C/EBP-homologous protein, indicating the role of Ex-4 in modulating unfolded protein response for protecting neurons from ischemic damage [56]
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Close to 68,000 had type 2 diabetes, while just over 17,600 were overweight or obese with heart disease but did not have type 2 diabetes
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