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Although Bcr-Abl inhibitors such as imatinib, nilotinib, and dasatinib are effective in CML therapy 7,8,9 , the acquisition of the T315I mutation of BCR-ABL in patients causes the resistance to most tyrosine kinase inhibitors (TKI), leading to poor outcomes
Total glutathione lysis reagent and GSSG lysis reagent, which contains alkylating agent N-ethylmaleimide (25 mM) were prepared following manufactures protocol and added to respective wells along with blank for background
Keep a list of all medications, supplements, and foods you consume regularly, and share it with your doctor
The Harriet Lane Handbook E-Book: The Harriet Lane Handbook E-Book
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