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Although lifestyle interventions (low-calorie diets and exercise) are still the cornerstone of weight management, weight loss achieved through this approach is extremely difficult to sustain in the long term, particularly due to physiological adaptations that reduce the energy expended or increase appetite to compensate for the missing calories
[11] Xu, E., Ye, E., Han, Y., et al
This structured monitoring ensures the treatment remains safe as the patients body adapts to the medication
For weight management, the appetite and fullness effects are often the biggest change
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