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The prognosis of advanced HCC is poor, the median overall survival (OS) time is roughly 12 months (Ren et al., 2020) and only systemic therapy can improve survival time
This severely limited nutrient supply explains why disc injuries heal so poorly compared to muscle tears or even bone fractures
The pipeline is promising, but availability is not yet set
It participates in the conversion of homocysteine to methionine and the metabolism of methylmalonic acid, both crucial for energy production at the cellular level
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