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* Correspondence: Jana Ruda-Kucerova, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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Proposed mechanisms of its action include inactivation of the melanogenic enzyme, tyrosinase, influencing the switch from eumelanin to phaeomelanin
After AT1R is coupled with PLC-1, it activates and promotes the change of CaM expression and conformation, thus regulating intracellular Ca 2+ concentration and calcium-regulated kinase activity, resulting in a series of biological effects
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