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In practice, some prescribers may use semaglutide off-label in selected patients who have insulin resistance, excess weight, or features of metabolic syndrome, but this should only happen under medical supervision
Addition of second drug: Many patients experience secondary failure as T2D progresses, and require addition of a second drug
However, experts say that for most people, the benefits of improving blood sugar levels or reducing weight with Wegovy still outweigh the increased risks of certain vision problems
It tends to improve as the body adjusts
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