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While the mid-regions of both peptides interact with the top of TM1/ECD stalk, the ECD, ECL1 and the top of TM2, exendin-4 exhibits more persistent interactions in the simulations, particularly with the TM1/stalk and ECD (Supplementary Tables 1 and 3)
& Klotz, L.-O
And that doesn't mean Also lends itself to our understanding around safety, and we're going to get into all of that
Pros: No Side effects except I was gassy and bloated during the first week or so but that went away
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