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At the end of the original 72-week study, people on the highest dose of either medication were randomized into two arms: the treatment group taking a once-daily dose of orforglipron and a placebo control group
In summary, the GLP-1 receptor remains an interesting and noteworthy target for the pharmacotherapy of central nervous system diseases, not only those related to neurodegeneration and substance abuse, but GLP-1RA drugs may also prove effective as adjunctive therapies in the treatment of mood disorders such as depression
As with any medication or procedure, side effects are possible though they are usually mild
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Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment
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