The mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems
By inhibiting oxidative phosphorylation (OXPHOS), which induces mitochondrial hyperpolarization and subsequently stimulates ROS production [23], the oxidation of palmitoylcarnitine (C16-carnitine) produces more ROS in mitochondria than carbohydrates [24]
Adenosine, an EU-approved wrinkle-reducing active, works on the smoothness and elasticity that pigment alone does not account for
We expect to see more pack trade-offs in potato chips, soft drinks and cold cereal but we also see outsized pack trade-offs in coffee and granola, which implies two emerging trends in the GLP-1 population: a general decrease in snacking, even for snacks usually considered healthy, and overall collateral damage that is spreading to categories that should not be greatly affected by GLP-1 status. In addition to their impact on the retail food and beverage market, oral GLP-1 medications are expected to account for 20% of total GLP-1 drug sales by 2031, with a pill market that is estimated to grow from $3.2 billion in 2025 to $34.3 billion in 2031, according to GlobalData.