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Interestingly, studies showed that vitamin D supplementation improved behavioral symptoms in ASD children, including stereotypy, irritability, and eye contact, as evaluated by the Autism Behavior Checklist and/or the Childhood Autism Rating Scale 39,40,41

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Mice with hyperbilirubinemia due to Gilberts syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPAR

Bearing in mind that a recent review stated that nonalcoholic fatty liver disease (NAFLD) is very frequent in PCOS patients, and that the combination of PCOS with obesity and IR is a dangerous cocktail that, over time, triggers not only NALFD but also the occurrence of type II diabetes (40, 41), as an additional feature, we also evaluated the HIE in our patients (23)