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If your appetite suppression has noticeably weakened, if food noise has returned to pre-medication levels, if you can eat larger meals without discomfort, and if the characteristic feeling of the medication has faded, these point toward receptor level changes rather than simple metabolic adaptation
In a randomized placebo-controlled trial that included 30 individuals with tinnitus and no-to-mild hearing loss, 100 mg acai extract daily for three months reduced self-reported tinnitus-related discomfort, but did not lower anxiety levels or improve markers of oxidative stress more than placebo
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