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This pharmacovigilance system is crucial for identifying previously unrecognised adverse effects, monitoring the safety profile of newly licensed medications like Mounjaro, and detecting rare but serious reactions that may not have been apparent during clinical trials
Such alterations were also associated with inhibition of cytochrome c oxidase (CcOX) activity and microtubule network disassembly, which are considered hallmarks of nitric oxide (NO) toxicity, indicating that NO, rather than the depletion of GSH per se, is the primary mediator of cell damage
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