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Anti-inflammatories, including vitamin C can interact with B12 injections

However, these do have to be prescribed and administered by a healthcare professional, and are more likely to be given to people who have lifelong conditions affecting their ability to absorb B12 or who are at higher risk of consistent deficiency

Allergic reactions are uncommon, but if you were to experience symptoms like swelling of the tongue or throat, hives, or difficulty breathing after an injection, that could indicate an allergy and you should seek medical help immediately

[13] In a newly diagnosed vitamin B 12 -deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 g (1 mg) per day are given to replenish the body's depleted cobalamin stores