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Healthcare providers administer semaglutide through weekly injections
According to Jain et al
Thus, our results support conducting preclinical studies of semaglutide (and other GLP1R agonist) on THC and randomized clinical trials to evaluate the therapeutic benefits of semaglutide in CUD in individuals with obesity or T2D as well as in patients with CUD who dont have these co-morbid conditions
Additional considerations include: Concurrent medications : Certain drugs (including some antiretrovirals, immunosuppressants, and diuretics) may increase pancreatitis risk Structural pancreatic abnormalities : Pancreatic divisum or other anatomical variants may predispose to inflammation Family history : Hereditary pancreatitis syndromes, though rare, substantially elevate risk NICE guidance (NG28) on type 2 diabetes management emphasises individualised treatment selection based on patient characteristics and comorbidities
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