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Systolic (SBP) and diastolic blood pressure (DBP) were also consistently reduced by incretin-based drugs, ranging from 3.1 and 0.57 mmHg with liraglutide 3.0 mg to 9.2 and 5.1 mmHg with retatrutide, respectively
In vitro studies reported that high doses of ascorbate can have prooxidant effects
Glia 63 , 5165
While animal studies have provided foundational insights into the neurobiological consequences of chronic ethanol exposure, human research faces unique challenges stemming from the heterogeneity of human populations, ethical limitations, and the multifactorial nature of alcoholism and mood disorders (Vena et al
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