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The 20 mg dose served as a mid-to-high exposure level within these escalation protocols, supporting subsequent phase 3 PIONEER trial development focusing on fixed 3, 7, and 14 mg maintenance doses
Washing requires only resuspension of the resin in an appropriate wash buffer followed by a brief period to allow the resin to settle
Tendons are dense, fibrous connective tissues that attach muscle to bone, and they are notoriously slow to heal due to their limited blood supply and low metabolic activity
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