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By reshaping the metabolic phenotype of tumor cells, miRNAs enhance their survival, metastatic potential, and resistance to therapy [110]

however, new technologies like chemical modifications (e.g., cyclic peptides), nanoparticles, and specific absorption enhancers (like SNAC in Ozempic's oral version, Rybelsus) are making oral delivery possible for certain therapeutic peptides, like semaglutide (Wegovy/Ozempic), transforming them from injections to convenient tablets, though many supplements lack strong evidence

Examples of conjugated proteins include: Glycoproteins , incorporating polysaccharide prosthetic groups (e.g

ABCC2) in MDCKII-MRP2 membrane vesicles