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Maquart F X, Bellon G, Chaqour B, et al
As in the LEAN study, the primary outcome is histologic resolution of NASH without worsening of fibrosis after 72 weeks of treatment, while secondary outcomes include improvement in liver fibrosis (1 stage) with no worsening of NASH, NAFLD activity score, as well as multiple serum markers of fibrosis
Current research provides some reassurance that GLP-1 agonists are not inherently dangerous for those with IBS, and in fact may offer additional gut benefits like reduced pain and improved barrier function
The goal is gentle mixing, not a cocktail shaker
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