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The subcutaneous tissue in these areas provides appropriate depth for medication depot formation, allowing for the sustained release profile necessary for once-weekly dosing

The observations here from both the tri-agonist and coagonist treatments are interesting, as numerous studies have indicated that GIPR activation results in weight gain, not weight loss

Back Staton, T (3 May 2017) 'Novo's diabetes medication Victoza keeps growing, despite Lilly's market-share creep', Fierce Pharma

The Phase 2 results are striking Across several trials, body weight, blood sugar and liver fat improved more in the higher-dose groups, and the pattern was consistent