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Marine Environmental Research
Thats likely due to the impact of female sex hormones (including changes during pregnancy and postpartum), especially estrogen, which increases the cholesterol content in bile
STEP 3 showed 16.0% with intensive lifestyle intervention
Mechanistically they do not overlap (GLP-1 agonists work through appetite and gastric emptying, this works on adipocyte lipogenesis and NAD+), and the mouse data specifically showed fat loss without reduced food intake, so they are not redundant
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