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We confirm that co-treatment with 5FU and mitochondrial inhibitors, particularly CI inhibitors IACS-010759 (a specific CI inhibitor under clinical evaluation 51 ) and metformin hydrochloride (a treatment for diabetes that inhibits CI 52 ), increases growth arrest and death in CRC cells (Fig
With injectable protocols, some patients report visible improvements in skin quality within 2-4 weeks
10.1146/annurev-physiol-022516-034227 28 InkerL
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