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Reconstitution 3-step visual Reconstitute , add bacteriostatic water down the wall of the vial Measure , use the calculator (section 8) to compute the required volume Store , refrigerator 2 to 8 C, protect from light Detailed protocol What you will need: A vial of AOD-9604 (5 mg lyophilizate) 2 to 2.5 ml of bacteriostatic water (contains 0.9 % benzyl alcohol, a preservative that prevents bacterial growth) Insulin syringe 1 ml / 29G Procedure: Allow the vial of AOD-9604 to reach room temperature (15 to 20 min)

The biologic effects of growth factor-toxin conjugates in models of vascular injury depend on dose, mode of delivery, and animal species

Hydroxocobalamin injection should be given only intramuscularly

Assessments were performed at 1, 4, 7, 15, 30, 90, 180, and 360 days after injury