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doi:10.1161/CIR.0000000000001423 Centers for Disease Control and Prevention
Metformin activates AMPK, a key energy regulator that promotes autophagy, reduces senescent cells, and mimics the effects of caloric restrictionsupporting healthy aging and cellular repair
Dosing without UV will prime melanocytes but will not produce the visible darkening that confirms successful melanogenesis
But inadequate protein intake leads to muscle loss, which reduces metabolic rate, which undermines the entire purpose of the medication
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