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A ~40% reduction in oxygen consumption rate was found in the RINm5F cells from 2 h till 17 h during MG treatment (Fig

In competitive binding assays, MT-2 demonstrates high affinity for the receptors MC1R, MC3R, MC4R, and MC5R with Ki values in the sub-nanomolar to low-nanomolar range, while minimal affinity was measured for MC2R Dorr et al., 199600160-3)