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They are expensive, and access to them may be limited due to shortages, including for patients with type 2 diabetes, while some people use these drugs for "cosmetic" purposes
After treatment, the expression of StAR and CYP17A1 was significantly downregulated (Figure 3CE)
This can leave patients facing the full brunt of the costs, making it a more expensive route to weight management for some
A 9mg dose could potentially capture the small additional benefit of higher dosing while maintaining most of the tolerability advantage of 8mg
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