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5.2.3 Bottlenecks and opportunities in clinical translation While ferroptosis-targeted strategies show promise in OA models, the translation to clinical settings remains hindered by key limitations in safety, efficacy, and delivery
Microdosing Schedule Key Notes & Considerations: The standard schedule reflects widely published titration guidelines: start with 2.5 mg once weekly, increasing by 2.5 mg every four or more weeks until a maintenance dose is reached that is appropriate for the indication
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