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Some healthcare providers may prescribe both off-label in select cases, but this requires careful patient selection, comprehensive cardiovascular screening, and close monitoring for additive side effects including increased heart rate, blood pressure changes, and gastrointestinal symptoms
The trial showed that participants who received semaglutide experienced an average weight loss of around 15% compared to the placebo group, which only achieved around 2.4% weight loss
The heart rate picture requires more attention
Third, demand exceeds manufacturing capacity
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