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People without obesity will continue to need joint replacements at the same rate as before
Constipation and bowel stasis GLP-1 receptor agonists slow gastric motility
The UBC study analyzed insurance claim records from 20062020 for about 16 million US patients who had been prescribed semaglutide or liraglutidethe two main active ingredients in GLP-1sor bupropion-naltrexone to see how many patients from each group developed a gastrointestinal condition
However, pairing GLP-1 drugs with DPP-4 inhibitors is generally avoided since both act on the same pathway, resulting in overlapping effects without meaningful added benefits
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