semaglutide for liver disease Shows Major Promise Treating Serious Landmark Study Finds Semaglutide Effectively

Receptor Pharmacology PMC open access Central MCR mechanism confirmed by SHU 9119 antagonism Central effects of Melanotan II shown to be abolished by SHU 9119, a non-selective MC3R/MC4R antagonist, confirming receptor-mediated central MCR mechanism

Methods This retrospective, database study used Optums de-identified Clinformatics Data Mart Database to identify glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment-nave adult patients with type 2 diabetes (T2D) initiating semaglutide QW, dulaglutide, liraglutide, or exenatide QW between January 1, 2018 and April 30, 2019

The risk is small, but still very real

Major health organizations encourage replacing saturated fats (like butter and fatty meats) with unsaturated fats, including polyunsaturated fats