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History of Medullary Thyroid Carcinoma (MTC) or MEN 2 Individuals with a history of medullary thyroid carcinoma (a type of thyroid cancer) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid semaglutide due to the potential risk of worsening these conditions
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Darkening of moles and new pigmented lesions: Existing moles/freckles darken and new ones can appear the central reason ongoing skin surveillance is mandatory and any changing lesion needs a dermatologist
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