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This strategy improves the metabolic profile of obese mice without the adverse side effects associated with estrogen therapy (pages 18471856)

Medication can be a powerful tool, but it works best as part of a supervised plan that also protects muscle, supports nutrition, and addresses the factors that contributed to weight gain in the first place

While not a listed adverse reaction in the SmPC, persistent forceful vomiting can theoretically lead to Mallory-Weiss tearssmall lacerations in the oesophageal mucosa that may bleed

This dual action is why tirzepatide often shows greater weight loss in head-to-head comparisons