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This is lower than the approximately 39% GI event rate seen in clinical trials at the equivalent injectable initiation dose, likely because the daily peak concentration is lower than the weekly injection peak
Among them, GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) play central roles in regulating metabolism
Eli Lilly, the drugs manufacturer, announced the findings from its large Triumph-1 study on 21 May 2026
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