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A study in 2019 further revealed that lactate can promote the post-translational modification (PTM) of lysine residues in histones, that is, lactylation, thus mediating regulatory effects at the transcriptional level [15]
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(2012) demonstrated that copper-free GHK increased stemness and proliferative potential of basal epidermal cells, with significantly increased p63-positive and PCNA-positive (proliferating cell nuclear antigen) cells in GHK-treated skin equivalents
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