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A recent study found that administering DADS at doses of either 40 or 80 mg/kg produced therapeutic effects comparable to those of imipramine, a prescription antidepressant at a dose of 10 mg/kg, in treating mice with depression-like behaviors induced by LPS (160)
The ISR-dependent gene Trib3 was notably upregulated in the liver of cysteine-deprived animals
Contact with certain toxic substances , such as lead or mercury
TPE, therapeutic plasma exchange
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